Predictive biomarker for efficient adjuvant therapies by evaluating metastatic ability

Mammographic density: a potential monitoring biomarker for adjuvant and preventative breast cancer endocrine therapies

Increased mammographic density (MD) has been shown beyond doubt to be a marker for increased breast cancer risk, though the underpinning pathobiology is yet to be fully elucidated. Estrogenic activity exerts a strong influence over MD, which consequently has been observed to change predictably in response to tamoxifen anti-estrogen therapy, although results for other selective estrogen receptor...

Predictive ability of C-reactive protein for stroke

CDX2 - A Predictive Biomarker in Stage II Colon Cancer for Adjuvant Chemotherapy?

Copyright: © 2017 Huang K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Citation: Huang K, Jennifer W. CDX2 A Predictive Biomarker in Stage II Colon Cancer for Adjuvant Chemotherapy?. Colorec Cancer....

Adjuvant therapies for HIV-associated neurocognitive disorders

OBJECTIVE HIV-associated neurocognitive disorder (HAND) is a frequent and heterogeneous complication of HIV, affecting nearly 50% of infected individuals in the combined antiretroviral therapy (cART) era. This is a particularly devastating statistic because the diagnosis of HAND confers an increased risk of HIV-associated morbidity and mortality in affected patients. While cART is helpful in th...

Testing for Unconditional Predictive Ability

This chapter provides an overview of pseudo-out-of-sample tests of unconditional predictive ability. We begin by providing an overview of the literature, including both empirical applications and theoretical contributions. We then delineate two distinct methodologies for conducting inference: one based on the analytics in West (1996) and the other based on those in Giacomini and White (2006). T...